| ncRNA name | hsa-miR-181a |
| ncRNA Category | miRNA |
| Disease name | cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | human lens epithelial cell line HLE-B3 |
| Methods | RNAi, flow cytometry, qRT-PCR, ELISA |
| Expression pattern | associated |
| Functional description | miR-181a knockdown may protect HLE‑B3 cells against H2O2‑induced apoptosis in vitro. The molecular mechanisms involved in the protective effects of miR‑181a silencing may involve the suppression of CASP3, BAX and COX‑2 expression, and the inhibition of MDA generation. |
| PubMed ID | 29484431 |
| Year | 2018 |
| Title | Downregulation of microRNA-181a attenuates hydrogen peroxide-induced human lens epithelial cell apoptosis in vitro. |
| Drug-related ncRNA | NO |
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